Study Overview
Very little is known about using antidepressants in patients living with bipolar depression. Antidepressants can be very effective in people with depression and can also be prescribed by a GP.
What is the ASCEnD study?
In this study, we will use a combination of an antidepressant (sertraline) and an antipsychotic (aripiprazole) and compare this combination with an antipsychotic medication called quetiapine. Quetiapine is a common treatment for people experiencing depression in bipolar disorder.
ASCEnD study medications
All three medications are already used in the NHS, but we want to find out if using a sertraline/aripiprazole combination will be beneficial in reducing depressive symptoms in people with bipolar disorder.
The ASCEnD study process
To do this, we are looking for 270 patients with bipolar who are currently experiencing a depressive phase from across the England to take part in the study.
Click the button below to find out more about eligibility requirements and recruitment processes.
